| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10593713 | Bioorganic & Medicinal Chemistry Letters | 2015 | 4 Pages |
Abstract
Synthesis of pseudosaccharin amines as KV1.5 blockers led to the discovery of potent antagonists such as 17d. These compounds had potent pharmacodynamic activity, however, showed off-target activities such as hemodynamic effects.31
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Authors
John Lloyd, Heather J. Finlay, Alexander Kover, James Johnson, Zulan Pi, Ji Jiang, James Neels, Cullen Cavallaro, Ruth Wexler, Mary Lee Conder, Hong Shi, Danshi Li, Huabin Sun, Anjaneya Chimalakonda, Christine Huang, Mark Salvati, Paul Levesque,