| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10593729 | Bioorganic & Medicinal Chemistry Letters | 2012 | 5 Pages |
Abstract
Phosphoinositide-3-kinase (PI3K) is an important target for cancer therapeutics due to the deregulation of its signaling pathway in a wide variety of human cancers. We describe herein a novel series of imidazo[1,2-a]pyrazines as PI3K inhibitors.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
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Authors
Sonia MartÃnez González, Ana Isabel Hernández, Carmen Varela, Sonsoles RodrÃguez-ArÃstegui, Rosa MarÃa Alvarez, Ana Belén GarcÃa, Milagros Lorenzo, Virginia Rivero, Julen Oyarzabal, Obdulia Rabal, James R. Bischoff, Maribel Albarrán,