Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10593746 | Bioorganic & Medicinal Chemistry Letters | 2012 | 4 Pages |
Abstract
A series of tetracyclic diterpenoids bearing α-methylenelactone group were synthesized from stevioside. Some of them exhibited significant cytotoxicity against all the six tumor cell lines with the IC50 values ranging from 0.09 to 5.71 μM.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yao-fu Zeng, Jia-qiang Wu, Lian-yong Shi, Ke Wang, Bin Zhou, Yong Tang, Da-yong Zhang, Yang-chang Wu, Wei-yi Hua, Xiao-ming Wu,