| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10593814 | Bioorganic & Medicinal Chemistry Letters | 2012 | 4 Pages |
Abstract
The synthesis and SAR of a novel series of 4-azabenzoxazole histamine H3 antagonists is described. Introduction of substituted phenyl, pyridyl and fused heterocyclic groups to the 6-position of the 4-azabenzoxazole core gave a series of compounds with good H3 antagonist activity in both ex vivo and in vivo assays.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ning Shao, Robert Aslanian, Robert E. Jr., Shirley M. Williams, Ren-Long Wu, Joyce Hwa, Christopher Sondey, Jean Lachowicz, Anandan Palani,