| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10593975 | Bioorganic & Medicinal Chemistry Letters | 2011 | 7 Pages |
Abstract
Pyrazole analogs with small R1â² alkyl and R3 pyrimidine groups improve potency and selectivity against BACE2. Thiophene analogs are more selective against cathepsin D.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Michael S. Malamas, Jim Erdei, Iwan Gunawan, Keith Barnes, Yu Hui, Matthew Johnson, Albert Robichaud, Ping Zhou, Yinfa Yan, William Solvibile, Jim Turner, Kristi Yi Fan, Rajiv Chopra, Jonathan Bard, Menelas N. Pangalos,