| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10594153 | Bioorganic & Medicinal Chemistry Letters | 2012 | 5 Pages |
Abstract
This manuscript reports the identification of a potent, selective GR antagonist with oral bioavailability. CORT118335 exhibited excellent efficacy at a low dose in an olanzapine-induced weight gain study in rats.
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Authors
Hazel J. Hunt, Nicholas C. Ray, George Hynd, Jon Sutton, Mohammed Sajad, Elizabeth O'Connor, Shahadat Ahmed, Peter Lockey, Steve Daly, Gerry Buckley, Robin D. Clark, Robert Roe, Christine Blasey, Joe Belanoff,