| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10594163 | Bioorganic & Medicinal Chemistry Letters | 2011 | 6 Pages |
Abstract
A series of 4-azetidinyl-1-aryl-cyclohexanes as potent CCR2 antagonists with high selectivity over activity for the hERG potassium channel is discovered through divergent SARs of CCR2 and hERG.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Xuqing Zhang, Heather Hufnagel, Thomas Markotan, James Lanter, Chaozhong Cai, Cuifen Hou, Monica Singer, Evan Opas, Sandra McKenney, Carl Crysler, Dana Johnson, Zhihua Sui,