| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10594212 | Bioorganic & Medicinal Chemistry Letters | 2012 | 7 Pages |
Abstract
Two highly selective sub-series of DFG-out leads for PYK2, an indole-urea and a pyrazole-urea were identified, and found to bind with different interactions in the hinge region of PYK2.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Samit K. Bhattacharya, Gary E. Aspnes, Scott W. Bagley, Markus Boehm, Arthur D. Brosius, Leonard Buckbinder, Jeanne S. Chang, Joseph Dibrino, Heather Eng, Kosea S. Frederick, David A. Griffith, Matthew C. Griffor, Cristiano R.W. Guimarães,