| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10594237 | Bioorganic & Medicinal Chemistry Letters | 2012 | 4 Pages |
Abstract
New 5-acetamido-substituted melatonin derivatives were efficiently synthesized in excellent yields via Knoevenagel condensation.The relative binding affinity of new synthesized compounds to MT3 receptor was tested via enzymatic assays and the X-ray structures of the most potent compounds were determined in complex with MT3.
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Organic Chemistry
Authors
Maria S. Volkova, Katherine C. Jensen, Natalia A. Lozinskaya, Sergey E. Sosonyuk, Marina V. Proskurnina, Andrew D. Mesecar, Nikolay S. Zefirov,