Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10594331 | Bioorganic & Medicinal Chemistry Letters | 2012 | 4 Pages |
Abstract
Novel bicyclic iminosugar derivatives fused thiazolidin-4-one were conveniently synthesized by double Pummerer rearrangements, and their HIV reverse transcriptase (RT) inhibitory activities were preliminary examined. The notable anti-HIV-RT activity demonstrated that such bicyclic azasugars hold potential as a new kind of HIV-RT inhibitors.
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Authors
Hua Chen, Tianyu Yang, Sinan Wei, Hongzhi Zhang, Rui Li, Zhanbin Qin, Xiaoliu Li,