| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10594397 | Bioorganic & Medicinal Chemistry Letters | 2012 | 5 Pages |
Abstract
This paper details exploration of a class of triazole-based cathepsin S inhibitors examplified by compound 6 originally reported by Ellman and coworkers. SAR studies involving modifications across the whole inhibitor provide a perspective on the strengths and weaknesses of this class of inhibitors.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Neil Moss, Zhaoming Xiong, Mike Burke, Derek Cogan, Donghong A. Gao, Kathleen Haverty, Alexander Heim-Riether, Eugene R. Hickey, Raj Nagaraja, Matthew Netherton, Kathy O'Shea, Philip Ramsden, Racheline Schwartz, Daw-Tsun Shih, Yancey Ward, Erick Young,