Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10594431 | Bioorganic & Medicinal Chemistry Letters | 2012 | 4 Pages |
Abstract
Optimisation of a series of biaryl sulphonamides resulted in the identification of compound 7 which demonstrated dose-dependent and strain-specific inhibition of monocyte recruitment in a thioglycollate-induced peritonitis model of inflammation.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Chris A. Smethurst, Nicola Bevan, Carl Brooks, Amanda Emmons, Peter J. Gough, Claudette Mookherjee, Kitty Moores, Simon Peace, Joanne Philp, Val Piercy, Steve P. Watson, Mara Zippoli,