| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10594436 | Bioorganic & Medicinal Chemistry Letters | 2012 | 4 Pages |
Abstract
A series of fluorinated tetrahydropyrano[3,2-c]chromenes and dihydropyrano[3,2-b]pyran derivatives have been synthesized and their in vitro cytotoxic activities have been determined in cervical cancer cell line (HeLa), human breast adenocarcinoma cell line (MDA-MB-231 and MCF-7) and human alveolar adenocarcinoma cell line (A549). Compounds 4g, 4k, 4p showed a very potent activity against MDA-MB-231, and 4c, 4p showed promising activity against MCF-7, while compounds 4c, 4g, 4p showed moderate activity against HeLa.
Keywords
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Organic Chemistry
Authors
Narender Reddy Emmadi, Krishnaiah Atmakur, Ganesh Kumar Chityal, Sujitha Pombala, Jagadeesh Babu Nanubolu,