| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10594490 | Bioorganic & Medicinal Chemistry Letters | 2012 | 6 Pages |
Abstract
A series of novel pyrazole peptidomimetics was synthesized from 3-aryl-1-arylmethyl-1H-pyrazole-5-carboxylic acid and amino acid ester. Compounds 5e and 5k suppress effectively the growth of A549 lung cancer cells through combination of apoptosis, autophagy and cell cycle arrest.
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Authors
Ying-Rui Liu, Ji-Zhuang Luo, Pan-Pan Duan, Jing Shao, Bao-Xiang Zhao, Jun-Ying Miao,