Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10594535 | Bioorganic & Medicinal Chemistry Letters | 2012 | 6 Pages |
Abstract
The design, synthesis and SAR of novel tetrahydrocarbazole derivatives having 5-HT6 receptor antagonist activity is presented. The racemic compound 15e was found to possess desirable pharmacokinetic properties, adequate brain penetration and activity in animal models of cognition.
Related Topics
Physical Sciences and Engineering
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Authors
Ramakrishna V.S. Nirogi, Jagadishu Babu Konda, Ramasastry Kambhampati, Anil Shinde, Thrinath Reddy Bandyala, Parandhama Gudla, Kiran Kumar Kandukuri, Pradeep Jayarajan, Vishwottam Kandikere, P.K. Dubey,