| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10594551 | Bioorganic & Medicinal Chemistry Letters | 2012 | 9 Pages |
Abstract
Lead optimization of tropane-derived HTS hits driven by traditional SAR and X-ray crystallography led to the identification of clinical candidate 12i (XL888).
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Authors
Joerg Bussenius, Charles M. Blazey, Naing Aay, Neel K. Anand, Arlyn Arcalas, TaeGon Baik, Owen J. Bowles, Chris A. Buhr, Simona Costanzo, Jeffrey K. Curtis, Steven C. DeFina, Larisa Dubenko, Timothy S. Heuer, Ping Huang, Christopher Jaeger, Anagha Joshi,