Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10594574 | Bioorganic & Medicinal Chemistry Letters | 2012 | 6 Pages |
Abstract
β-Secretase inhibitor 4f showed an enzyme Ki of 13 nM and a cellular IC50 value of 21 nM. A molecular model of 4f provided insight into the ligand-binding site interactions.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Arun K. Ghosh, Satyendra Pandey, Sudhakar Gangarajula, Sarang Kulkarni, Xiaoming Xu, Kalapala Venkateswara Rao, Xiangping Huang, Jordan Tang,