Synthesis of 3-(1-alkyl/aminoalkyl-3-vinyl-piperidin-4-yl)-1-(quinolin-4-yl)-propan-1-ones and their 2-methylene derivatives as potential spermicidal and microbicidal agents

Article ID	Journal	Published Year	Pages	File Type
10594694	Bioorganic & Medicinal Chemistry Letters	2012	4 Pages	PDF

Abstract

Biological activity: Tartarate salt of 3-(1-pentyl-3-vinyl-piperidin-4-yl)-1-quinolin-4-yl-propan-1-one (27) was found to be more active spermicidal agent than nonoxynol-9.

Keywords

Spermicides Trichomonas vaginalis HeLa cells Microbicides

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

Preview

Synthesis of 3-(1-alkyl/aminoalkyl-3-vinyl-piperidin-4-yl)-1-(quinolin-4-yl)-propan-1-ones and their 2-methylene derivatives as potential spermicidal and microbicidal agents

Authors

Rishi Ranjan Pandey, Akansha Srivastava, Richa Malasoni, Arshi Naqvi, Ashish Jain, Jagdamba Prasad Maikhuri, Sarvesh Paliwal, Gopal Gupta, Anil Kumar Dwivedi,