Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10594717 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
Neutral fluorescent active di-pyrene modified γ-cyclodextrin (1) was synthesized in order to discriminate with single and double strand DNA (ssDNA and dsDNA, respectively) with high selectivity. The binding and selectivity of 1 for dsDNA was indicated by increase of the fluorescent intensity in an addition of dsDNA. On the other hand, an increase of fluorescent intensity of 1 was not recognized in an addition of ssDNA.
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Authors
Akane Takeda, Kazuhiko Akimoto, Yoshihiko Kondo, Fumio Hamada,