Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10594742 | Bioorganic & Medicinal Chemistry Letters | 2010 | 5 Pages |
Abstract
Structure-activity relationships, X-ray crystallography and oral in vivo anti-tumor activity for a series of 8-THP-DHI dual TIE-2/VEGF-R2 inhibitors are reported.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Robert L. Hudkins, Allison L. Zulli, Ted L. Underiner, Thelma S. Angeles, Lisa D. Aimone, Sheryl L. Meyer, Daniel Pauletti, Hong Chang, Elena V. Fedorov, Steven C. Almo, Alexander A. Fedorov, Bruce A. Ruggeri,