| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10594754 | Bioorganic & Medicinal Chemistry Letters | 2010 | 6 Pages |
Abstract
Using a vHTS based on a pharmacophore alignment on known β3-adrenoceptor ligands, a set of intriguing β-adrenoceptor ligands was identified, optimization of which resulted in a selective and potent human β2-AR antagonist.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Stefan Tasler, Roland Baumgartner, Andrea Aschenbrenner, Astrid Ammendola, Kristina Wolf, Tanja Wieber, Josef Schachtner, Marcus Blisse, Udo Quotschalla, Peter Ney,