Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10594941 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
5-F substitution of an aminothiazole moiety within a series of thrombopoietin receptor agonists leads to potent agents with an improved hepatic safety profile in rodent toxicology studies.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Amy S. Antipas, Laura C. Blumberg, William H. Brissette, Matthew F. Brown, Jeffrey M. Casavant, Jonathan L. Doty, James Driscoll, Thomas M. Harris, Christopher S. Jones, Sandra P. McCurdy, Eric McElroy, Mark Mitton-Fry, Michael J. Munchhof,