| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10594943 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
A synthesis of novel pyrazolopyridine, benzopyranopyrazolopyridine, and oxygen-bridged pyrazolo-, tetrazolo-, benzimidazo-, and thiazolopyrimidines via Hantzsch- and Biginelli-like condensations has been developed. The ability of these compounds to inhibit Eg5 activity has been examined. The results indicate that synthetic manipulations in the monastrol thiourea moiety are inefficient.
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Chemistry
Organic Chemistry
Authors
Jan Svetlik, Lucia Veizerová, Thomas U. Mayer, Mario Catarinella,