| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10594964 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
Benzofuran-substituted urea analogs have been identified as novel P2Y1 receptor antagonists. Structure-activity relationship studies around the urea and the benzofuran moieties resulted in compounds having improved potency. Several analogs were shown to inhibit ADP-mediated platelet activation.
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Authors
Reema K. Thalji, Nambi Aiyar, Elizabeth A. Davenport, Joseph A. Erhardt, Lorena A. Kallal, Dwight M. Morrow, Shobha Senadhi, Cynthia L. Burns-Kurtis, Joseph P. Jr.,