| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10595001 | Bioorganic & Medicinal Chemistry Letters | 2010 | 5 Pages |
Abstract
A series of novel semicarbazones based 2,5-disubstituted-1,3,4-oxadiazoles possessing four vital structural features (A) hydrophobic aryl ring system, (HBD) hydrogen binding domain, (D) electron donor moiety and (C) distal aryl ring required for anticonvulsant activity are disclosed. The aryl semicarbazones have been found to possess anticonvulsant activity through GABA mediation.
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Authors
Harish Rajak, Ravitas Deshmukh, Ravichandran Veerasamy, Ajay Kumar Sharma, Pradeep Mishra, Murli Dhar Kharya,