Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10595102 | Bioorganic & Medicinal Chemistry Letters | 2013 | 8 Pages |
Abstract
The synthesis of several analogues of ma'edamines A and B are reported. The synthesized compounds were tested on hormone receptor positive and HER2 positive breast cancer cell lines by MTT assay. MED-114, 115, 117, 119, 120, 124, 128 and 131 were found to be equally active as Lapatinib on HER2 +ve cell line SKBR3.
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Authors
Sanjay Saha, Ch. Venkata Ramana Reddy, Shili Xu, Saranya Sankar, Nouri Neamati, Balaram Patro,