Article ID Journal Published Year Pages File Type
10595169 Bioorganic & Medicinal Chemistry Letters 2012 4 Pages PDF
Abstract
The structural analogs of epibatidine and epiboxidine (±)-10-(±)-17, characterized by the 7-azabicylo[2.2.1]hept-2-ene ring, were prepared taking advantage of Pd-catalyzed cross-coupling reactions. The compounds were assayed for binding affinity at neuronal α4β2 and α7 nicotinic acetylcholine receptor subtypes.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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