Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10595208 | Bioorganic & Medicinal Chemistry Letters | 2012 | 4 Pages |
Abstract
A series of compounds with a diphenyl ether nucleus were synthesized and screened for antitubercular activity against Mycobacteriumtuberculosis H37Rv, among which compound 6c was the most potent with MIC value of 4 μg/mL. It was further found to be effective in attenuating the pathological changes caused by BCG infection in vivo.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yinghong Yang, Zhenling Wang, Jianzhong Yang, Tao Yang, Weiyi Pi, Wei Ang, Yanni Lin, Yuanyuan Liu, Zicheng Li, Youfu Luo, Yuquan Wei,