| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10595272 | Bioorganic & Medicinal Chemistry Letters | 2012 | 5 Pages |
Abstract
Facile synthesis of two new series of tetracyclic azepine and oxazocine analogs is described. These analogs were evaluated for their potential as MAPKAP-K2 (MK2) inhibitors and several were found to be potent at inhibiting MK2 with a non-ATP competitive binding mode.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ashwin U. Rao, Dong Xiao, Xianhai Huang, Wei Zhou, James Fossetta, Dan Lundell, Fang Tian, Prashant Trivedi, Robert Aslanian, Anandan Palani,