| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10595413 | Bioorganic & Medicinal Chemistry Letters | 2013 | 5 Pages |
Abstract
A novel series of N-type calcium channel inhibitors have been discovered. Optimization of potency and HT-ADME properties provides 4-aminocyclopentapyrrolidines with analgesic efficacy after oral dosing.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Xenia Beebe, Clinton M. Yeung, Daria Darczak, Shashank Shekhar, Timothy A. Vortherms, Loan Miller, Ivan Milicic, Andrew M. Swensen, Chang Z. Zhu, Patricia Banfor, Jill M. Wetter, Kennan C. Marsh, Michael F. Jarvis, Victoria E. Scott, Michael R. Schrimpf,