| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10595447 | Bioorganic & Medicinal Chemistry Letters | 2013 | 5 Pages |
Abstract
Synthesis of procyanidin B2 and B3 gallate derivatives, 3-O-gallate, 3â³-O-gallate, and 3,3â³-di-O-gallate, were synthesized using equimolar condensation mediated by Yb(OTf)3. Synthesized compounds showed significant antitumor effects against human prostate PC-3 cell lines. Their activities were weaker than well-known EGCG and prodelphinidin B3.
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Authors
Manato Suda, Miyuki Katoh, Kazuya Toda, Kiriko Matsumoto, Koichiro Kawaguchi, Sei-ichi Kawahara, Yasunao Hattori, Hiroshi Fujii, Hidefumi Makabe,