| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10595486 | Bioorganic & Medicinal Chemistry Letters | 2013 | 8 Pages |
Abstract
The advancement of a series of ligand efficient 2-amino-[1,2,4]triazolo[1,5-a]pyridines, initially identified from high-throughput screening, to a JAK2 inhibitor with pharmacodynamic activity in a mouse xenograft model is disclosed.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
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Authors
Michael Siu, Richard Pastor, Wendy Liu, Kathy Barrett, Megan Berry, Wade S. Blair, Christine Chang, Jacob Z. Chen, Charles Eigenbrot, Nico Ghilardi, Paul Gibbons, Haiying He, Christopher A. Hurley, Jane R. Kenny, S. Cyrus Khojasteh, Hoa Le, Leslie Lee,