| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10595501 | Bioorganic & Medicinal Chemistry Letters | 2013 | 4 Pages |
Abstract
A series of alkyloxyquinoline derivatives has been developed to evaluate the relationship between P-gp potency and lipophilicity. The results show a satisfactory lipophilicity-activity correlation although a series of derivatives showing higher P-gp potency is needed in order to confirm this hypothesis.
Related Topics
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Organic Chemistry
Authors
Marialessandra Contino, Laura Zinzi, Mariangela Cantore, Maria Grazia Perrone, Marcello Leopoldo, Francesco Berardi, Roberto Perrone, Nicola Antonio Colabufo,