| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10595619 | Bioorganic & Medicinal Chemistry Letters | 2009 | 5 Pages |
Abstract
The novel spiro[isobenzofuran-1,2â²-pyran] structure is proved to be an effective scaffold for diversification of SGLT2 inhibitors and a number of compounds with single digit nanomolar potency and high selectivity have been synthesized.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Binhua Lv, Baihua Xu, Yan Feng, Kun Peng, Ge Xu, Jiyan Du, Lili Zhang, Wenbin Zhang, Ting Zhang, Liangcheng Zhu, Haifeng Ding, Zelin Sheng, Ajith Welihinda, Brian Seed, Yuanwei Chen,