| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10595641 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
A series of novel oxazaphosphorine prodrugs of PMEA is disclosed. l-valine methyl ester (7c) demonstrated highly potent anti-HBV activity, excellent stability in human plasma and release of the parent compound PMEA in human microsomes.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Peng Lu, Jiangxia Liu, Yuya Wang, Xiaoyan Chen, Yushe Yang, Ruyun Ji,