| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10595648 | Bioorganic & Medicinal Chemistry Letters | 2009 | 5 Pages |
Abstract
New small molecule inhibitors of HCV were discovered by screening a small library of indoline alkaloid-type compounds. An automated assay format was employed which allowed identification of dimerization inhibitors of core, the capsid protein of the virus. These compounds were subsequently shown to block production of infectious virus in hepatoma cells.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Wanguo Wei, Cuifang Cai, Smitha Kota, Virginia Takahashi, Feng Ni, A. Donny Strosberg, John K. Snyder,