Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10595691 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
A panel of cinnamoyl anthranilates were investigated for their antifibrotic activity through their ability to reduce collagen formation stimulated by the cytokine transforming growth factor-β. The most active compound was shown to reduce albuminuria in a hypertensive rat model of progressive type II diabetes.
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Authors
Steven C. Zammit, Alison J. Cox, Renae M. Gow, Yuan Zhang, Richard E. Gilbert, Henry Krum, Darren J. Kelly, Spencer J. Williams,