Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10595693 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
A new class of chimeric molecules have been developed. These are based on polyphenols like catechin and epicatechin and monocyclic β-lactams. The two units are joined via a triazole linker using the 'Click Chemistry' conditions. The compounds showed good to weak antibacterial activity against Escherichia coli as well as moderate inhibition of RNase A.
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Authors
Basab Roy, Arindam Chakraborty, Sudip K. Ghosh, Amit Basak,