Article ID Journal Published Year Pages File Type
10595760 Bioorganic & Medicinal Chemistry Letters 2011 4 Pages PDF
Abstract
The design and synthesis of an agarose resin functionalized with a Gram-negative quorum sensing (QS) signaling molecule analogue is described. The modified resin was utilized in affinity pull-down assays to successfully isolate QscR, a LuxR-type QS receptor from Pseudomonas aeruginosa. This resin may facilitate the identification of novel QS signal receptors using affinity chromatography techniques.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
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