| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10595925 | Bioorganic & Medicinal Chemistry Letters | 2013 | 7 Pages |
Abstract
The structure-based design, synthesis, and SAR of a novel series of Aurora kinase inhibitors based on the 5H-benzo[c][1,8]naphthyridin-6-one scaffold 1 are described.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![SAR and evaluation of novel 5H-benzo[c][1,8]naphthyridin-6-one analogs as Aurora kinase inhibitors](/preview/png/10595925.png "First Page Preview: SAR and evaluation of novel 5H-benzo[c][1,8]naphthyridin-6-one analogs as Aurora kinase inhibitors")
Authors
Srinivasa Karra, Yufang Xiao, Xiaoling Chen, Lesley Liu-Bujalski, Bayard Huck, Amanda Sutton, Andreas Goutopoulos, Ben Askew, Kristopher Josephson, Xuliang Jiang, Adam Shutes, Vikram Shankar, Tom Noonan, Gaianne Garcia-Berrios, Rong Dong,