Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10596001 | Bioorganic & Medicinal Chemistry Letters | 2013 | 9 Pages |
Abstract
Based on a series of phenylaminopyrimidinebased (PAP) derivatives that can inhibit BCR-ABL tyrosine kinase, a seven-point pharmacophore model was developed using Phase software. A statistically significant 3D-QSAR model was also yielded based on this pharmacophore model.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jing Cui, Rao Fu, Li-Hua Zhou, Sheng-Ping Chen, Guang-Wu Li, Shen-Xian Qian, Shu Liu,