Article ID Journal Published Year Pages File Type
10596047 Bioorganic & Medicinal Chemistry Letters 2013 4 Pages PDF
Abstract
Compound 2a was found to possess an excellent glucose lowering activity, more potent than glibenclamide-a well known antidiabetic sulphonylurea drug. In addition, the compound is a very good inhibitor of ALR1 and ALR2.
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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Preview
Dual action spirobicycloimidazolidine-2,4-diones: Antidiabetic agents and inhibitors of aldose reductase-an enzyme involved in diabetic complications
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