| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10596097 | Bioorganic & Medicinal Chemistry Letters | 2013 | 4 Pages |
Abstract
The cytotoxic agent 2 displays potent antimalarial properties towards drug-sensitive as well as drug-resistant strains of Plasmodium falciparum. It concentrates in erythrocytes where it lowers the concentration of glutathione and displays adequate permeability characteristics across the CACO-2 monolayer.
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Authors
Ravi S.P. Singh, Umashankar Das, Jennifer M. Auschwitz, Susan E. Leed, Mark R. Hickman, Jonathan R. Dimmock, Jane Alcorn,