Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10596108 | Bioorganic & Medicinal Chemistry Letters | 2013 | 7 Pages |
Abstract
The Letter reports synthesis, release and pharmacological profile of the promising co-drug (DTH) of diacerein with antioxidant thymol based on the reports of involvement of oxidative stress in the pathophysiology of osteoarthritis. It is characterized by superior anti-inflammatory/anti-arthritic effects, better absorption, longer duration of action with lower ulcerogenic potential than diacerein.
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Authors
Suneela Dhaneshwar, Vriha Patel, Dipmala Patil, Gourav Meena,