Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10596109 | Bioorganic & Medicinal Chemistry Letters | 2013 | 4 Pages |
Abstract
A series of bisulfite adducts derived from representative transition state inhibitors (dipeptidyl aldehydes and α-ketoamides) was synthesized and shown to exhibit inhibitory activity against Norwalk virus 3C protease in vitro, as well as anti-norovirus activity in a cell-based replicon system.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sivakoteswara Rao Mandadapu, Mallikarjuna Reddy Gunnam, Kok-Chuan Tiew, Roxanne Adeline Z. Uy, Allan M. Prior, Kevin R. Alliston, Duy H. Hua, Yunjeong Kim, Kyeong-Ok Chang, William C. Groutas,