Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10596213 | Bioorganic & Medicinal Chemistry Letters | 2013 | 5 Pages |
Abstract
Compound 8, a farnesyl substituted at 9-O-position of berberine, could significantly enhance the cytotoxic activity of human cancer HepG2 and HT-29 cell lines, the presence of lipophilic farnesyl substituents with moderate sizes might be crucial for the optimal anticancer activity.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Chih-Yu Lo, Lin-Chen Hsu, Min-Shin Chen, Yi-Jing Lin, Lih-Geeng Chen, Cheng-Deng Kuo, Jin-Yi Wu,