Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10596340 | Bioorganic & Medicinal Chemistry Letters | 2009 | 8 Pages |
Abstract
Modifications of the thiazole core, linkers, and substituents on the right-hand phenyl are investigated. Compound 37c demonstrated a dose-dependent decrease in the plasma desaturation index in C57BL/6J mice on a non-fat diet after 7 days of oral administration.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yoshikazu Uto, Tsuneaki Ogata, Yohei Kiyotsuka, Yuriko Miyazawa, Yuko Ueno, Hitoshi Kurata, Tsuneo Deguchi, Makiko Yamada, Nobuaki Watanabe, Toshiyuki Takagi, Satoko Wakimoto, Ryo Okuyama, Masahiro Konishi, Nobuya Kurikawa, Keita Kono, Jun Osumi,