| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10596365 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
A novel aspirin analogue, 5, which inhibits platelet aggregation, contains ester groups which can simultaneously interact with Arg120 and Tyr385 at the active site of PGHS, whilst positioning its acetyl group close to Ser530.
Related Topics
Physical Sciences and Engineering
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Organic Chemistry
Authors
Ahmed Alagha, Edelmiro Moman, Mauro F.A. Adamo, Kevin B. Nolan, Anthony J. Chubb,