Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10596404 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
A series of potent Cathepsin L inhibitors with good selectivity with respect to other cysteine Cathepsins is described and SAR is discussed with reference to the crystal structure of a protein-ligand complex.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Nabil Asaad, Paul A. Bethel, Michelle D. Coulson, Jack E. Dawson, Susannah J. Ford, Stefan Gerhardt, Matthew Grist, Gordon A. Hamlin, Michael J. James, Emma V. Jones, Galith I. Karoutchi, Peter W. Kenny, Andrew D. Morley, Keith Oldham, Neil Rankine,