| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10596405 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
Two modifications of metomidate [(R)-1] without influence on inhibition of [131I]4-I-(R)-1 binding to 11β-hydroxylase reduced inhibitory potency at the GABAA receptor: substitution of the phenyl ring with HOCH2- and rigid attachment of the phenyl residue to the chiral centre.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Erika Atucha, Friedrich Hammerschmidt, Ilse Zolle, Werner Sieghart, Michael L. Berger,